The Illizarov Method uses Ilizarov's Principle of DISTRACTION OSTEOGENESIS (osteo=bone, genesis=formation). This refers to the induction of new bone between bone surfaces that are pulled apart in a gradual, controlled manner. The distraction initially gives rise to NEOVASCULARISATION (Neo=new, vascular=relating to blood), which is what actually stimulates new bone formation. In addition, there is simultaneous histogenesis (histo=tissue) of muscles, nerves and skin. In bone diseases (osteomyelitis, fibrous dysplasia, pseudo-arthrosis) this new bone replaces pathological bone with normal bone. This is a revolutionary concept diseases for which earlier there was no treatment are now successfully treated using the Ilizarov Method.